产品货号：
Z34460
中文名称：
STIM1 Purified抗体
英文名称：
Anti-STIM1 Purified Antibody (Clone#CDN3H4)
产品规格：
0.1mg(C100)
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-STIM1 Purified Antibody (Clone#CDN3H4) |
| 指标别名 | D11S4896E;GOK;STIM1;stromal interaction molecule 1 |
| 克隆性 | Monoclonal |
| 检验物种 | rat,human,mouse |
| 应用范围 | IP,WB,IHC,ICC |
| 基因名称 | STIM1 |
| 克隆号 | CDN3H4 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | Synthetized peptide (C-terminal cytoplasmic part of STIM1).The mouse monoclonal antibody CDN3H4 reacts with a cytoplasmic epitope of human and rodent STIM1,a 84kDa essential and conserved regulator of store-operated Ca2+ channel function. |
| 成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
| 纯化方式 | Purified by protein-A affinity chromatography. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Store at 2～8℃.Do not freeze. |
| 背景资料 | STIM1 (stromal interacting molecule;also known as GOK) acts as a sensor of calcium depletion within the endoplasmic reticulum and transduces the signal to Orai1,the presumptive CRAC channel at the plasma membrane.Following decrease of luminal calcium concentration,STIM1 oligomerizes and induces Orai1 to enable entry of extracellular calcium into the cytoplasm.However,the precise mechanism of STIM1-Orai1 interaction has not been elucidated yet.Many questions also remain to be solved around STIM1 functional distribution.It turns out that STIM1 associates with growing ends of microtubules and is involved in endoplasmic reticulum tubule extension. |
| Uniprot ID | G0XQ39 |
| 基因名全称 | Stromal interaction molecule 1 |
| 推荐稀释比 | Immunocytochemistry:Methanol-aceton fixation;positive control:HeLa human cervix carcinoma cell line. Immunohistochemistry (paraffin sections):5μg/mL. Western blotting:1μg/mL;positive control:RBL rat basophilic leukemia cell line;both reducing and non-reducing conditions. |
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